Clinical Significance of the Interleukin 24 mRNA Level in Head and Neck Squamous Cell Carcinoma and Its Subgroups: An In Silico Investigation

Figure 5

(a) The forest plot of 4 data sets evaluating the standard mean difference (SMD) of Interleukin 24 (IL24) mRNA expression between nasopharyngeal carcinoma (NPC) tissues and noncancer tissues based on Gene Expression Omnibus (GEO). (b) The summary receiver operating characteristic curves analysis of IL24 mRNA for discriminating NPC from noncancer tissues based on GEO database. (c, d) Sensitivity and specificity values of the included studies. The sensitivity and specificity values of the included studies were 0.44 (95% CI = 0.31−0.58) and 0.86 (95% CI = 0.69−0.94), respectively. (e) Prior probability and postprobability positive and negative of the included studies. The prior probability, postprobability positive, and postprobability negative reached 20%, 43%, and 14%, respectively (LR: likelihood ratio).

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