Comparison of Involved Field Radiotherapy versus Elective Nodal Irradiation in Stage IIIB/C Non-Small-Cell Lung Carcinoma Patients Treated with Concurrent Chemoradiotherapy: A Propensity Score Matching Study

Table 1

Pretreatment and treatment characteristics for all patients and per elective nodal irradiation status.

Covariate	All patients (N = 1048)	ENI (N = 379)	IFRT (N = 669)	value
Median age, y (range)	62 (29–79)	61 (29–79)	64 (34–79)	0.56
Age group, y (%)
≤70 years	927 (88.5)	328 (86.5)	599 (89.5)	0.43
>70 years	121 (11.5)	51 (13.5)	70 (10.5)
Gender (%)
Male	654 (62.4)	235 (62.0)	419 (62.6)	0.73
Female	394 (37.6)	144 (38.0)	250 (37.4)
KPS (%)
90–100	751 (71.7)	269 (71.0)	482 (72.0)	0.64
70–80	297 (28.3)	110 (29.0)	187 (28.0)
Histology (%)
AC	567 (54.1)	212 (55.9)	355 (53.1)	0.39
SCC	481 (45.9)	167 (44.1)	314 (46.9)
T-stage
1-2	361 (34.4)	116 (30.6)	245 (36.6)	0.28
3-4	687 (65.6)	263 (69.4)	424 (63.4)
N-stage
2	531 (50.7)	195 (51.5)	336 (50.2)	0.55
3	517 (49.3)	184 (48.5)	333 (49.8)
Tumor stage (%)
IIIB	617 (58.9)	217 (57.3)	400 (59.8)	0.67
IIIC	431 (41.1)	162 (42.7)	269 (40.2)
Chemotherapy cycles (%)
2-3	854 (81.4)	272 (71.8)	582 (87.0)	0.002
1	194 (18.6)	107 (28.2)	87 (13.0)
Radiotherapy technique (%)
3D-CRT	385 (36.7)	157 (41.4)	228 (34.1)	0.24
IMRT	663 (63.3)	222 (58.6)	441 (65.9)

ENI: elective nodal irradiation; IFRT: involved-field radiotherapy; KPS: Karnofsky performance score; AC: adenocarcinoma; SCC: squamous cell cancer; T: tumor; N: node; 3D-CRT: 3-dimensional conformal radiotherapy; IMRT: intensity-modulated radiotherapy.