A Novel Prognostic Index Based on the Analysis of Glycolysis-Related Genes in Head and Neck Squamous Cell Carcinomas

Table 3

Introduction and summary of eight genes constructing the prognostic model.

Gene symbol	Full name	Encoding protein	Function	Risk coefficient
GPR87	G protein-coupled receptor 87	A cell surface G protein-coupled receptor	Glycolysis-related proteins	0.007433349
HMMR	Hyaluronan-mediated motility receptor	Hyaluronan-mediated motility receptor	Regulate homeostasis, mitosis, and meiosis	0.096146079
HK1	Hexokinase-1	A member of the hexokinases	The first rate-limiting enzyme in glycolysis	0.008524517
JMJD8	Jumonji C domain-containing 8	A member of the Jumonji C domain-containing (JMJD) protein family	Regulating glycolysis metabolism by interacting with pyruvate kinase M2	−0.047903542
EXT2	Exostosin-2	A member of the exostosin family	An enzyme that harbors glycosyltransferase activities	0.011711524
STC1	Stanniocalcin 1	A glycosylated peptide hormone	Uncouples the process of oxidative phosphorylation	0.026067236
STC2	Stanniocalcin 2	A glycosylated peptide hormone	Regulating glucose homeostasis	0.034033864
KIF2A	Kinesin family protein 2A	A member of the kinesin-13 family	Glycolysis-related proteins	−0.134494599