Prognostic Value of a Three-DNA Methylation Biomarker in Patients with Soft Tissue Sarcoma

Figure 2

Violin plots of methylation level at a single CpG site for STS patients with short- and long-term survival in the training dataset. Here, short-term survival refers to a survival time that was less than or equal to 3 years, and long-term survival refers to a survival time for more than 3 years. Blue violin plots are for STS patients with short-term survival, and green violin plots are for patients with long-term survival. The dotted line through the black dot represents the median, the range of the white box is from the lower quartile to the upper quartile, the thin white line represents the 95% confidence interval, and the outer shape is the density. The two on the left are violin plots of methylation distribution of cg19804488 for patients with short-term survival and long-term survival. Similarly, the two in the middle correspond to cg20542822, and the two on the right correspond to cg07898500. The Mann–Whitney U test showed that there was a significant difference in long-term and short-term patients with respect to the methylation levels of the three methylation sites.