Patterns and Prevalence of Germline BRCA1 and BRCA2 Mutations among High-Risk Breast Cancer Patients in Jordan: A Study of 500 Patients

Table 1

Patient characteristics (n = 517).

Characteristics		Number	(%)
Age at diagnosis (years)	Median	39
	Range	19–78
Hormonal status	ER-positive	392	75.8
	PR-positive	375	72.5
	ER- or PR-positive	420	81.2
	ER- and PR-negative	97	18.8
HER2 status	HER2-positive	133	25.7
	HER2-negative	318	61.5
	Unknown	66	12.7
Triple-negative		57	11.0
Positive family history of breast cancer		441	85.3

ER: rstrogen receptors; PR: progesterone receptors; HER2: human epidermal growth factor receptor.