Research Article

High Expression of COL17A1 Predicts Poor Prognosis and Promotes the Tumor Progression via NF-κB Pathway in Pancreatic Adenocarcinoma

Figure 4

Upregulation of COL17A1 promoted the proliferation and invasion of PDAC cells. The verification of COL17A1 overexpression was evaluated by RT-qPCR (a) and western blotting in PACN-1 and SW1990 cells (b, c). Outcomes of overexpression of COL17A1 with regard to proliferation and migration were evaluated by wound healing (d, e) and CCK-8 (f, g) assays. (h, i) The transwell assay measured the outcomes of COL17A1 overexpression on the invasion. Results shown are the mean ± SD (, , and ; the experiments were repeated at least three times). COL17A1-OE: transfected with COL17A1 overexpressing plasmids.