Prognostic Significance of the Tumor-Stromal Ratio in Invasive Breast Cancer and a Proposal of a New Ts-TNM Staging System

Table 3

Definition of the TNM and Ts-TNM staging system.

TNM stage	T	N	M	TNM stage	Ts	Ts-TNM stage
I	T1	N0	M0	I	Ts0	I
II	T0	N1	M0		Ts1	II
	T1	N1	M0	II	Ts0	II
	T2	N0	M0		Ts1	III
	T2	N1	M0	III	Ts0	III
	T3	N0	M0		Ts1	IV
III	T0	N2	M0
	T1	N2	M0
	T2	N2	M0
	T3	N1-2	M0
	T4	N0–2	M0
	Any T	N3	M0

TNM, tumor node metastasis; Ts-TNM, tumor-stroma tumor node metastasis; T, tumor; N, node; Ts, tumor-stroma; Ts1, low TSR (high stroma); Ts0, high TSR (low stroma).