Equipping the American Joint Committee on Cancer Staging for Resectable Pancreatic Ductal Adenocarcinoma with Tumor Grade: A Novel Staging System

Table 2

Univariate and multivariate analysis for overall survival of patients in the training set.

Characteristics	Univariate analysis value	Multivariate analysis
		HR (95% CI)	value
Age, yrs (＜65)
≥65	＜0.001	1.175 (1.102–1.254)	＜0.001
Sex (male)
Female	0.507
Location (head)
Body and tail	0.088
Other	0.608
Year of diagnosis (2004–2009)
2010–2015	＜0.001	0.638 (0.597–0.681)	＜0.001
Grade (low grade)
High grade	＜0.001	1.333 (1.250–1.423)	＜0.001
Examined lymph nodes (＜15)
≥15	＜0.001	0.800 (0.748–0.856)	＜0.001
Extrapancreatic invasion 8th T stage (T1)	＜0.001	1.199 (1.097–1.310)	＜0.001
T2	＜0.001	1.340 (1.200–1.473)	＜0.001
T3	＜0.001	1.549 (1.394–1.722)	＜0.001
8th N stage (N0)
N1	＜0.001	1.336 (1.235–1.445)	＜0.001
N2	＜0.001	1.793 (1.639–1.961)	＜0.001
7th AJCC stage (IA)
IB	＜0.001
IIA	＜0.001
IIB	＜0.001

Abbreviations: HR, hazard ratio; CI, confidence interval.