Sex Hormones and Inflammation Role in Oral Cancer Progression: A Molecular and Biological Point of View

Figure 2

Schematic representation of the relation between oral squamous cell carcinoma (OSCC), inflammation, and periodontitis. The figure represents the different mechanisms involved in the development of the OSCC in relation to inflammation. The chronic one is correlated to periodontitis disease and may lead to genetic and epigenetic changes like cytokine, SNPs. This mutation involved mainly IL-α and IL-β which are overexpressed.