Upregulation of Nei-Like DNA Glycosylase 3 Predicts Poor Prognosis in Hepatocellular Carcinoma

Figure 3

Kaplan–Meier survival curves according to NEIL3 expression in HCC patients stratified by TNM stage, tumor differentiation, HBsAg expression, or cirrhosis. (a, b) Advanced TNM stage patients with high NEIL3 expression had a worse OS () and DFS () compared with advanced TNM stage patients with low NEIL3 expression. (c, d) Poor tumor differentiation patients with high NEIL3 expression had a worse OS () and DFS () compared with the poor tumor differentiation patients with low NEIL3 expression. (e) HBsAg positive patients with high NEIL3 expression had a worse OS () compared with HBsAg positive patients with low NEIL3 expression. (f) cirrhosis patients with high NEIL3 expression had a worse DFS () compared with cirrhosis positive patients with low NEIL3 expression. NEIL3, Nei-like DNA glycosylase; HCC, hepatocellular carcinoma; OS, overall survival; DFS, disease-free survival.

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