Survivin Regulates Bad Gene Expression by Binding to Its Promoter and Modulates Cell Cycle and Apoptosis in Esophageal Carcinoma Cell

Figure 4

The effect of Bad overexpression on the apoptosis of esophageal carcinoma cell. Apoptotic rate of the UP_Bad group was significantly higher compared with the BC and NC groups. Data are presented as the means ± standard deviation from triplicate experiments. BC: blank control; NC, UP, and UP_Bad: cells in these groups were transfected with negative control and overexpression plasmid, respectively. Statistically significant differences compared to BC and NC groups are indicated ( < 0.05,  < 0.01).