Expression of the CLCA4 Gene in Esophageal Carcinoma and Its Impact on the Biologic Function of Esophageal Carcinoma Cells

Table 2

Univariate and multivariate Cox regression models for estimating the overall survival.

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Age (<60 vs. ≥60)	0.514 (0.347–1.647)	0.628	2.314 (1.345–3.547)	0.884
Tumor size (<5 vs. ≥5)	0.422 (0.214–0.847)	0.254	0.363 (0.094–0.921)	0.075
Gender (male vs. female)	0.647 (0.396–1.474)	0.341	0.421 (0.143–1.258)	0.069
T stage (I-II vs. III-IV)	1.671 (1.024–2.364)	0.044	0.694 (0.232–2.547)	0.055
Differentiation (moderate/high vs. low)	0.347 (0.127–0.843)	0.128	0.087 (0.029–0.647)	0.023
Lymph node metastasis (present vs. absent)	1.694 (1.235–2.684)	0.034	0.987 (0.348–1.874)	0.058
CLCA4 (low vs. high)	1.549 (1.146–2.647)	0.024	1.124 (0.654–2.367)	0.018

HR: hazard ratio; CI: confidence interval; , .