Research Article
SLCO4A1-AS1 Facilitates the Malignant Phenotype via miR-149-5p/STAT3 Axis in Gastric Cancer Cells
Figure 2
Silencing SLCO4A1-AS1, contrary to the overexpression of SLCO4A1-AS1, induced apoptosis and inhibited cell migration and invasion in gastric cancer. (a–d) Flow cytometry was used to detect the effect of SLCO4A1-AS1 exogenous overexpression or intervention on gastric cancer cell apoptosis. (e–h) The overexpression of SLCO4A1-AS1 promoted the migration of gastric cancer cells, while the low expression of SLCO4A1-AS1 had the opposite effect, as analyzed by the wound healing experiment (magnification ×100). (i–l) Transwell was used to detect the effect of SLCO4A1-AS1 overexpression or silencing on cell invasion ability (magnification ×200). Each experiment was repeated three times independently. and versus pc-control; and versus si-control.
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