Determination of Genetic and Epigenetic Modifications-Related Prognostic Biomarkers of Breast Cancer: Genome High-Throughput Data Analysis

Table 2

The key pathways for the differential between low and high expression of patients based on GSEA analysis.

Gene	Name	NES	value
HPDL	KEGG_FOCAL_ADHESION	−1.91198
	KEGG_DILATED_CARDIOMYOPATHY	−1.61559	0.002
	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	−1.64029	0.002075
	KEGG_ADHERENS_JUNCTION	−1.74735	0.002283
	KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION	−1.70915	0.002387
	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	−1.75006	0.006993
	KEGG_ABC_TRANSPORTERS	−1.5166	0.014141
	KEGG_MAPK_SIGNALING_PATHWAY	−1.66251	0.016713
	KEGG_TGF_BETA_SIGNALING_PATHWAY	−1.52333	0.04008
	KEGG_OOCYTE_MEIOSIS	1.754743
	KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	1.685132
	KEGG_CELL_CYCLE	1.639552
	KEGG_P53_SIGNALING_PATHWAY	1.51856	0.035503
	KEGG_OLFACTORY_TRANSDUCTION	1.609742	0.046472
SOX17	KEGG_OOCYTE_MEIOSIS	−1.58789	0.04814
	KEGG_JAK_STAT_SIGNALING_PATHWAY	1.797007
	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	1.865758	0.001481
	KEGG_ABC_TRANSPORTERS	1.455277	0.014463
	KEGG_RETINOL_METABOLISM	1.741166	0.017483
	KEGG_HEMATOPOIETIC_CELL_LINEAGE	1.564893	0.021195
	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	1.562236	0.023636
	KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	1.588887	0.029297
	KEGG_INSULIN_SIGNALING_PATHWAY	1.672106	0.038113
	KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	1.663495	0.039587
	KEGG_WNT_SIGNALING_PATHWAY	1.528532	0.04
	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	1.675274	0.043328
	KEGG_AXON_GUIDANCE	1.497392	0.047445