CircPTK2 (hsa_circ_0003221) Contributes to Laryngeal Squamous Cell Carcinoma by the miR-1278/YAP1 Axis

Figure 2

CircPTK2 knockdown inhibits cell proliferation and induces cell cycle arrest in LSCC cells. (a) RT-qPCR analysis was utilized to examine the knockdown efficiency of circPTK2 in SNU46 and SNU899 cells. (b, c) A CCK-8 assay was conducted to assess the viabilities of SNU46 and SNU899 cells. (d–f) Flow cytometry analysis was carried out to measure the cell cycle in LSCC cells. (g–i) The protein expression of Cyclin A1, Cyclin B1, and Cyclin D1 was measured by western blot analysis. .

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