circDENND4C Promotes Proliferation and Metastasis of Lung Cancer by Upregulating BRD4 Signaling Pathway

Figure 1

circDENND4C is upregulated in NSCLC. (a) RT-qPCR analysis of circDENND4C expression in NSCLC tissues. (b) Differential expression pattern of circDENND4C in NSCLC cell line. circDENND4C is highly expressed in A549 and H1299 cell lines. (c) The relative expression of circDENND4C in the nucleus and cytoplasm. The results showed that circDENND4C was mainly expressed in the cytoplasm. (d) RNA-FISH localizes circDENND4C in the cytoplasm of NSCLC. ^∗P < 0.05 and ^∗∗P < 0.01.