Research Article

circDENND4C Promotes Proliferation and Metastasis of Lung Cancer by Upregulating BRD4 Signaling Pathway

Figure 3

Downregulation of circDENND4C inhibits the proliferation and invasion of NSCLC in vivo. (a) sh-Ctrl and sh-circDENND4C subcutaneous transplanted tumor volume. (b) Tumor weight change curve. (c) PCR to detect the relative RNA expression of circDENND4C in subcutaneous tumors. (d) Statistics on the number of lung metastases. P < 0.05 and ∗∗P < 0.01.