Genetic Polymorphism rs6505162 in MicroRNA-423 May Not Be Associated with Susceptibility of Breast Cancer: A Systematic Review and Meta-Analysis

Table 2

Genotype distributions of miR-423 rs6505162 polymorphism.

First author	Year	Ethnicity	Country	Sample size (cases/controls)	No. of cases			Allele frequencies of cases		No. of controls			Allele frequencies of controls
					AA	AC	CC	A	C	AA	AC	CC	A	C
Kontorovich et al. [17]	2010	Caucasian	Israel	190/206	34	88	68	156	224	49	102	55	200	212
Smith et al. [18]	2012	Caucasian	Australia	179/174	60	95	24	215	143	42	80	52	164	184
Ma et al. [19]	2013	Asian	China	192/189	8	57	127	73	311	10	69	110	89	289
He et al. [20]	2015	Asian	China	450/450	16	142	292	174	726	22	129	299	173	727
Zhang et al. [21]	2015	Asian	China	382/189	20	131	231	171	593	10	69	110	89	289
Zhao et al. [22]	2015	Asian	China	114/189	5	30	79	40	188	10	69	110	89	289
Morales et al. [7]	2016	Caucasian	Chile	440/807	86	229	125	401	479	138	385	284	661	953
Saedi et al. [23]	2017	Asian	Iran	353/353	15	125	213	155	551	36	137	180	209	497
Tran Thi et al. [24]	2018	Asian	Vietnam	106/116	5	34	67	44	168	3	49	64	55	177
Mir et al. [25]	2018	Asian	Saudi Arabia	100/124	23	52	25	98	102	18	25	81	61	187
Mir et al. [26]	2019	Asian	Saudi Arabia	30/30	3	11	16	17	43	4	9	17	17	43
Pourmoshir et al. [27]	2020	Asian	Iran	153/153	59	46	48	164	142	67	63	23	197	109

Abbreviations: mir-423, microRNA-423.