Genetic Polymorphism rs6505162 in MicroRNA-423 May Not Be Associated with Susceptibility of Breast Cancer: A Systematic Review and Meta-Analysis

Table 3

Methodological quality of studies included in the final analysis based on the Newcastle–Ottawa Scale for assessing the quality of case-control studies.

Study	Selection (score)				Comparability (score)	Exposure (score)			Total score^b
	Adequate definition of patient cases	Representativeness of patient cases	Selection of controls	Definition of controls	Control for important factor or additional factor	Ascertainment of exposure (blinding)	Same method of ascertainment for participants	Non-response rate^a
Kontorovich et al. [17]	1	1	1	1	0	0	1	1	6
Smith et al. [18]	1	1	0	1	2	0	1	1	7
Ma et al. [19]	1	1	0	1	2	0	1	1	7
He et al. [20]	1	1	1	1	2	0	1	1	8
Zhang et al. [21]	1	1	1	1	2	0	1	1	8
Zhao et al. [22]	1	1	1	1	0	0	1	1	6
Morales et al. [7]	1	1	0	1	1	0	1	1	6
Saedi et al. [23]	1	1	0	1	1	0	1	1	6
Tran Thi et al. [24]	1	1	1	1	0	0	1	1	6
Mir et al. [25]	1	1	1	1	1	0	1	1	7
Mir et al. [26]	1	1	1	1	1	0	1	1	7
Pourmoshir et al. [27]	1	1	1	1	1	0	1	1	7

^aWhen there was no significant difference in the response rate between both groups based on a chi-squared test (), one point was awarded. ^bTotal score was calculated by adding up the points awarded in each item.