Research Article

TLR3 Serves as a Prognostic Biomarker and Associates with Immune Infiltration in the Renal Clear Cell Carcinoma Microenvironment

Table 2

Correlation of TLR3 expression and the prognosis of KIRC with different clinicopathological factors (Kaplan–Meier plotter).

Pathological parametersOverall survival
NHazard ratio value

Stage status
13980.6 (0.33–1.09)0.088
21830.11 (0.01–0.84)0.01
33320.47 (0.26–0.84)0.0093
41880.38 (0.22–0.67)5e−4

Gender
Female2840.36 (0.21–0.62)9.5e−5
Male9480.39 (0.26–0.56)3e−7

Race
White6900.41 (0.3–0.57)1.1e−8
Asian8NANA
Black/African-American1110.27 (0.06–1.25)0.073

Tumor grade
114NANA
23400.6 (0.31–1.16)0.12
35850.33 (0.2–0.53)2.1e−6
41740.4 (0.22–0.71)0.0013

Mutation burden
High2460.41 (0.23–0.72)0.0015
Low4370.34 (0.15–0.74)0.0042