Research Article
TLR3 Serves as a Prognostic Biomarker and Associates with Immune Infiltration in the Renal Clear Cell Carcinoma Microenvironment
Table 2
Correlation of TLR3 expression and the prognosis of KIRC with different clinicopathological factors (Kaplan–Meier plotter).
| Pathological parameters | Overall survival | N | Hazard ratio | value |
| Stage status | | | | 1 | 398 | 0.6 (0.33–1.09) | 0.088 | 2 | 183 | 0.11 (0.01–0.84) | 0.01 | 3 | 332 | 0.47 (0.26–0.84) | 0.0093 | 4 | 188 | 0.38 (0.22–0.67) | 5e−4 |
| Gender | | | | Female | 284 | 0.36 (0.21–0.62) | 9.5e−5 | Male | 948 | 0.39 (0.26–0.56) | 3e−7 |
| Race | | | | White | 690 | 0.41 (0.3–0.57) | 1.1e−8 | Asian | 8 | NA | NA | Black/African-American | 111 | 0.27 (0.06–1.25) | 0.073 |
| Tumor grade | | | | 1 | 14 | NA | NA | 2 | 340 | 0.6 (0.31–1.16) | 0.12 | 3 | 585 | 0.33 (0.2–0.53) | 2.1e−6 | 4 | 174 | 0.4 (0.22–0.71) | 0.0013 |
| Mutation burden | | | | High | 246 | 0.41 (0.23–0.72) | 0.0015 | Low | 437 | 0.34 (0.15–0.74) | 0.0042 |
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