Research Article
LncRNA PTPRG-AS1 Promotes the Metastasis of Hepatocellular Carcinoma by Enhancing YWHAG
Figure 6
Downregulation of PTPRG-AS1 inhibited HCC proliferation and invasion in vivo. (a) Tumor image and volume in nude mice injected subcutaneously with PLC-PRF-5 cell transfected with LV-NC and LV-shPTPRG-AS1 (n = 6). (b) qRT‐PCR was employed to estimate miRNA quantification of PTPRG-AS1 in nude mice of the above groups. (c) Tumor weight in nude mice injected subcutaneously with PLC-PRF-5 cell transfected with LV-NC and LV-shPTPRG-AS1. (d) Ki67 staining of tissues in different groups. (e) Number of metastases after PTPRG-AS1 downregulation by HE staining. qRT-PCR was employed to depict mRNA expression of E-cadherin (f) or vimentin (g) in nude mice of above groups. , .
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