Molecular Alterations of Circulating Cell-Free DNA in the Pathological Progression of Hepatocellular Carcinoma

Figure 3

The mutation burden in cfDNA of patients with CHB, LC, and HCC. (a) The average MMB of 40 HCC-related genes among CHB, LC, and HCC patients. (b) Mutation frequency in non-HCC (CHB + LC) and HCC patients. CHB, chronic hepatitis B; LC, liver cirrhosis; HCC, hepatocellular carcinoma; and MMB: molecular mutation burden.