Molecular Alterations of Circulating Cell-Free DNA in the Pathological Progression of Hepatocellular Carcinoma

Figure 5

The HCC diagnosis model based on gene mutation burden. (a) The average molecular mutation burden of 18 HCC-related genes among CHB, LC, and HCC patients. (b) The molecular mutation burden of mutated genes among CHB, LC, and HCC patients (18 genes). CHB, chronic hepatitis B; LC, liver cirrhosis; HCC, hepatocellular carcinoma; and MMB: molecular mutation burden.

(a)

(b)