Research Article
Molecular Alterations of Circulating Cell-Free DNA in the Pathological Progression of Hepatocellular Carcinoma
Table 1
Clinical characteristics of liver fibrosis and HCC patients.
| | Clinical characteristic | Liver fibrosis (n = 45) | HCC (n = 11) |
| | Age, median (range) | 36 (18–62) | 53 (28–68) | | Male, n (%) | 31 (68.9) | 10 (90.9) | | cfDNA (mean ± SD, ng/ml) | 16.4 ± 10.2 | 52.9 ± 35.4 | | AFP (mean ± SD, ng/ml) | 12.6 ± 25 | 659.0 ± 1028.0 | | Fibrosis stages (ISHAK), n (%) | | | | F0–2 | 27 (60.0) | — | | F3-4 | 10 (22.2) | | | F5-6 | 8 (17.8) | — | | Liver cirrhosis, n (%) | 8 (17.8) | 6 (54.5) |
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