Journal of Oncology

Research Article

HLA-DRB116:01 and HLA-DQB105:02 Alleles Influence the Susceptibility and Progression of Cutaneous Malignant Melanoma

Table 2

HLA class I alleles within the patient cohort.
HLA-AHealthy donor (N = 1272), n (AF)Melanoma patient (N = 474), N (AF)HLA-BHealthy donor (N = 1272), n (AF)Melanoma patient (N = 474), N (AF)HLA-CHealthy donor (N = 1272), n (AF)Melanoma patient (N = 474), N (AF)
A01:01127 (0.1)42 (0.089)B07:02117 (0.092)31 (0.065)C01:0241 (0.032)13 (0.027)
A01:022 (0.002)0 (0)B07:052 (0.002)0 (0)C02:0263 (0.05)36 (0.076)
A01:031 (0.001)0 (0)B07:065 (0.004)0 (0)C02:101 (0.001)0 (0)
A02:01312 (0.245)116 (0.245)B08:0164 (0.05)26 (0.055)C03:025 (0.004)0 (0)
A02:025 (0.004)2 (0.004)B13:0221 (0.017)10 (0.021)C03:0330 (0.024)12 (0.025)
A02:0514 (0.011)14 (0.03)B14:0121 (0.017)7 (0.015)C03:0422 (0.017)10 (0.021)
A02:062(0.002)1 (0.002)B14:0248 (0.038)25 (0.053)C04:01184 (0.145)57 (0.12)
A03:01121 (0.095)40 (0.084)B15:0139 (0.031)18 (0.038)C05:01143 (0.112)51 (0.108)
A03:027(0.006)2 (0.004)B15:038 (0.006)1 (0.002)C06:02103 (0.081)47 (0.099)
A11:0194 (0.074)36 (0.076)B15:162 (0.002)0 (0)C07:01159 (0.125)65 (0.137)
A23:0141 (0.032)12 (0.025)B15:179 (0.007)1 (0.002)C07:02131 (0.103)30 (0.063)
A24:02135 (0.106)38 (0.08)B15:188 (0.006)1 (0.002)C07:0414 (0.011)10 (0.021)
A24:033 (0.002)1 (0.002)B18:01131 (0.103)42 (0.089)C08:011 (0.001)0 (0)
A25:0122 (0.017)10 (0.021)B27:025 (0.004)4 (0.008)C08:0267 (0.053)31 (0.065)
A26:0145 (0.035)23 (0.049)B27:033 (0.002)0 (0)C08:030 (0)1 (0.002)
A29:017 (0.006)3 (0.006)B27:0533 (0.026)10 (0.021)C12:0224 (0.019)6 (0.013)
A29:0294 (0.074)32 (0.068)B27:072 (0.002)2 (0.004)C12:0377 (0.061)33 (0.07)
A30:0132 (0.025)10 (0.021)B35:0186 (0.068)18 (0.038)C14:0219 (0.015)6 (0.013)
A30:0242 (0.033)19 (0.04)B35:0215 (0.012)6 (0.013)C15:0247 (0.037)11 (0.023)
A30:040 (0)1 (0.002)B35:0319 (0.015)17 (0.036)C15:041 (0.001)0 (0)
A31:0125 (0.02)12 (0.025)B35:0811 (0.009)4 (0.008)C15:057 (0.006)2 (0.004)
A32:0143 (0.034)18 (0.038)B37:0114 (0.011)13 (0.027)C16:0196 (0.075)32 (0.068)
A33:0129 (0.023)15 (0.032)B38:0132 (0.025)16 (0.034)C16:0219 (0.015)8 (0.017)
A34:026 (0.005)0 (0)B39:0114 (0.011)6 (0.013)C16:040 (0)1 (0.002)
A66:016 (0.005)7 (0.015)B39:064 (0.003)3 (0.006)C17:0118 (0.014)8(0.017)
A68:0135 (0.028)9 (0.019)B40:0121 (0.017)10 (0.021)   
A68:029 (0.007)8 (0.017)B40:0214 (0.011)5 (0.011)   
A69:014 (0.003)2 (0.004)B40:063 (0.002)1 (0.002)   
A74:012 (0.002)0 (0)B41:0112 (0.009)9 (0.019)   
A80:017 (0.006)0 (0)B41:023 (0.002)2 (0.004)   
   B42:010 (0)1 (0.002)   
   B44:012 (0.002)0 (0)   
   B44:0270 (0.055)31 (0.065)   
   B44:03123 (0.097)40 (0.084)   
   B44:051 (0.001)1 (0.002)   
   B45:0120 (0.016)4 (0.008)   
   B47:013 (0.002)0 (0)   
   B48:011 (0.001)1 (0.002)   
   B49:0133 (0.026)19 (0.04)   
   B50:0136 (0.028)16 (0.034)   
   B50:024 (0.003)1 (0.002)   
   B51:01112 (0.088)42 (0.089)   
   B51:085 (0.004)3 (0.006)   
   B52:0120 (0.016)4 (0.008)   
   B53:0115 (0.01)5 (0.011)   
   B55:019 (0.007)3 (0.006)   
   B56:013 (0.002)1 (0.002)   
   B57:0129 (0.023)8 (0.017)   
   B58:0116 (0.013)2 (0.004)   
AF: allele frequency; n: number of observed alleles.