HLA-DRB116:01 and HLA-DQB105:02 Alleles Influence the Susceptibility and Progression of Cutaneous Malignant Melanoma

Table 4

Frequency of HLA-associated alleles in melanoma patients grouped according to clinical features.

	DRB116:01				DQB105:02
	%		Pc	OR	%		Pc	OR
Control	16 (0.013)				25 (0.02)
Breslow thickness
≤1.5 mm	9 (0.031)	0.023	Not significant		11 (0.038)	0.058	Not significant
>1.5 mm	10 (0.054)	0.001	0.035	4.46	12 (0.065)	0.001	0.017	3.44
Age at diagnosis
≤58 years	10 (0.042)	0.001	0.035	3.41	13 (0.054)	0.002	0.034	2.86
>58 years	9 (0.038)	0.004	Not significant		10 (0.043)	0.031	Not significant