Comparative Recurrence Analysis of Pancreatic Adenocarcinoma after Resection

Table 2

Pairwise comparison of survival for different tumor progression patterns.

Recurrence patterns		Whole cohort									Head
		OS			Aps			PFS			OS			Aps			PFS
		Mst	95%CI		Mst	95%CI		Mst	95%CI		Mst	95%CI		Mst	95%CI		Mst	95%CI
Local progression	Reference	29.37	24.47–39.57		15.93	11.07–25.03		8.97	6.40–10.57		27.60	24.47–37.23		15.93	9.13–21.53		9.13	6.90–10.80
	Liver-only metastasis	20.1	17.37–24.63	0.214	12.60	9.83–15.77	0.444	5.03	4.07–6.47	0.014	20.40	17.37–27.90	0.413	12.13	9.83–15.77	0.545	5.47	4.20–6.50	0.050
	Lung-only metastasis	17.33	15.33–52.57	0.582	14.70	14.00–30.43	0.581	5.47	2.80–7.47	0.680	17.30	15.33–33.30	0.413	14.70	14.00–17.10	0.443	2.87	2.63–10.60	0.720
	Other metastases	23.97	10.77–23.97	0.863	11.23	1.63–29.45	0.154	12.73	9.13–28.70	0.239	16.13	13.55–18.27	0.538	NA	NA	NA	12.13	10.24–15.27	0.532
	Local + distant metastasis	24.87	8.50–34.87	0.247	7.20	3.67–11.57	0.115	5.60	1.73–7.60	0.025	24.11	10.13–30.22	0.094	4.17	2.63–11.57	0.078	6.53	2.10–8.67	0.089
	Multiple metastases	17.50	11.20–19.50	0.006	9.20	8.10–12.63	0.023	5.70	3.80–8.30	0.017	17.50	13.80–19.50	0.049	9.20	8.10–12.63	0.121	5.70	2.70–8.63	0.023
Liver-only metastasis	Reference	20.1	17.37–24.63		12.60	9.83–15.77		5.03	4.07–6.47		20.40	17.37–27.90		12.13	9.83–15.77		5.47	4.20–6.50
	Lung-only metastasis	17.33	15.33–52.57	0.92	14.70	14.00–30.43	0.676	5.47	2.80–7.47	0.285	17.30	15.33–33.30	0.627	14.70	14.00–17.10	0.752	2.87	2.63–10.60	0.496
	Other metastases	23.97	10.77–23.97	0.562	11.23	1.63–29.45	0.225	12.73	9.13–28.70	0.036	16.13	13.55–18.27	0.452	NA	NA	NA	12.13	10.24–15.27	0.250
	Local + distant metastasis	24.87	8.50–34.87	0.47	7.20	3.67–11.57	0.286	5.60	1.73–7.60	0.931	24.11	10.13–30.22	0.479	4.17	2.63–11.57	0.171	6.53	2.10–8.67	0.773
	Multiple metastases	17.50	11.20–19.50	0.082	9.20	8.10–12.63	0.092	5.70	3.80–8.30	0.076	17.50	13.80–19.50	0.149	9.20	8.10–12.63	0.240	5.70	2.70–8.63	0.855
Lung-only metastasis	Reference	17.33	15.33–52.57		14.70	14.00–30.43		5.47	2.80–7.47		17.30	15.33–33.30		14.70	14.00–17.10		2.87	2.63–10.60
	Other metastases	23.97	10.77–23.97	0.678	11.23	1.63–29.45	0.125	12.73	9.13–28.70	0.309	16.13	13.55–18.27	0.558	NA	NA	NA	12.13	10.24–15.27	0.326
	Local + distant metastasis	24.87	8.50–34.87	0.491	7.20	3.67–11.57	0.436	5.60	1.73–7.60	0.061	24.11	10.13–30.22	0.553	4.17	2.63–11.57	0.408	6.53	2.10–8.67	0.799
	Multiple metastases	17.50	11.20–19.50	0.275	9.20	8.10–12.63	0.022	5.70	3.80–8.30	0.577	17.50	13.80–19.50	0.718	9.20	8.10–12.63	0.025	5.70	2.70–8.63	0.734
Other metastases	Reference	23.97	10.77–23.97		11.23	1.63–29.45		12.73	9.13–28.70		16.13	13.55–18.27		NA	NA		12.13	10.24–15.27
	Local + distant metastasis	24.87	8.50–34.87	0.334	7.20	3.67–11.57	0.686	5.60	1.73–7.60	0.016	24.11	10.13–30.22	0.273	4.17	2.63–11.57	NA	6.53	2.10–8.67	0.223
	Multiple metastases	17.50	11.20–19.50	0.108	9.20	8.10–12.63	0.998	5.70	3.80–8.30	0.002	17.50	13.80–19.50	0.617	9.20	8.10–12.63	NA	5.70	2.70–8.63	0.030
Local + distant metastasis	Reference	24.87	8.50–34.87		7.20	3.67–11.57		5.60	1.73–7.60		24.11	10.13–30.22		4.17	2.63–11.57		6.53	2.10–8.67
	Multiple metastases	17.50	11.20–19.50	0.701	9.20	8.10–12.63	0.958	5.70	3.80–8.30	0.910	17.50	13.80–19.50	0.879	9.20	8.10–12.63	0.770	5.70	2.70–8.63	0.637

NA, not available; other abbreviations as in Table 1.