Research Article

HOTAIR Contributes to Stemness Acquisition of Cervical Cancer through Regulating miR-203 Interaction with ZEB1 on Epithelial-Mesenchymal Transition

Figure 6

HOTAIR interacted with miR-203 to regulate the expression of ZEB1 and ZEB2. (a) Cells were treated with RNA interference targeting HOTAIR, and the miR-203 level was detected by qRT-PCR. The result indicated that miR-203 was negatively correlated with HOTAIR in HeLa cells. (b–d) Expression changes of ZEB1 and ZEB2 along with alteration of miR-203 was detected and analyzed by Western blot (b) and qPCR (c, d). NC, negative control. values represent significant difference based on Student’s t-test from three replicates (, ).
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