Review Article
ceRNAs in Cancer: Mechanism and Functions in a Comprehensive Regulatory Network
Table 2
ceRNAs in chemotherapy resistance.
| ceRNA | miRNA | Target | Chemotherapeutic agent | Cancer | Reference |
| LncPVT1 | miR-195 | SMAD3 | Paclitaxel | CC | [139] | | miR-216b | Beclin-1 | Cisplatin | NSCLC | [140] | | miR-152 | c-MET | Gemcitabine | Osteosarcoma | [141] | | miR-1207-5p/3p | SMAD | Gemcitabine | PC | [142] | | miR-143 | Hexokinase 2 | — | GBC | [143] | | miR-186-5p | YAP1 | — | HCC | [144] | lncRNA HOTAIR | miR-17-5p | Beclin1 | Sunitinib | Renal cancer | [145] | lncRNA HOXA-AS2 | miR-520c-3p | S100A4 | Adriamycin | AML | [146] | lncRNA GAS5 | miR-221 | — | Gemcitabine | PC | [147] |
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Abbreviation: CC: cervical cancer; NSCLC: nonsmall cell lung cancer; PC: pancreatic cancer; GBC: gallbladder cancer; HCC: hepatocellular carcinoma; AML: acute myelocytic leukemia. —: not available.
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