Antitumor Effects of Paeoniflorin on Hippo Signaling Pathway in Gastric Cancer Cells

<div>Paeoniflorin inhibits the migration and invasion of gastric cancer cells. (a) Left panel: migratory activity of MGC803 and SGC7901 cells after paeoniflorin treatments was detected by wound healing assay. 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354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,49.918,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,52.882,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,59.122,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> vs. control groups. The results are presented as the mean ± SD. (b) Invasion of MGC803 and SGC7901 cells treated with paeoniflorin was detected by transwell chambers assay. Right panel: quantitative results were shown for left panel. (c) The expression of TAZ and <i>β</i>-catenin in MGC803 and SGC7901 cells after paeoniflorin treatments was measured by western blotting analysis. Right panel: quantitative results were shown for left panel.</div>

Journal of Oncology

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Figure 2

Figure 2: Antitumor Effects of Paeoniflorin on Hippo Signaling Pathway in Gastric Cancer Cells 