DAP10 Predicted the Outcome of Pediatric B-Cell Acute Lymphoblastic Leukemia and Was Associated with the T-Cell Exhaustion

Figure 4

High expression level of DAP10 was associated with favorable survival. (a) Patients in high immune score and high stromal score groups showed higher expression level of DAP10. (b) Downregulation of DAP10 in B-ALL bone marrow compared to the normal individuals. (c) The results of western blot showed that DAP10 was hardly expressed in 10 pediatric ALL patients compared to 2 normal individuals. N: normal; P: patients. High expression level of DAP10 predicted favorable OS (d), EFS (e), and RFS (f).

(a)

(b)

(c)

(d)

(e)

(f)