Research Article

DAP10 Predicted the Outcome of Pediatric B-Cell Acute Lymphoblastic Leukemia and Was Associated with the T-Cell Exhaustion

Table 2

Clinical data of the two groups divided by the RNA level of DAP10.

DAP10 highDAP10 low

WBC count62.4 ± 13.943.5 ± 7.20.232
WBC >5041.7% (15/36)31.1% (19/61)0.294
Age7.3 ± 0.87.6 ± 0.60.753
Age ≥1030.6% (11/36)34.4% (21/61)0.695
BCR-ABL12.8% (1/36)3.3% (2/61)1.000
CNS3 at diagnosis8.3% (3/36)0.0% (0/61)0.048
High risk58.3% (21/36)60.7% (34/61)0.803
Relapse55.6% (20/36)82.0% (50/61)0.005
Tri 4/1021.2% (7/33)5.6% (3/54)0.038
TEL/AML111.1% (3/27)11.8% (6/51)1.000
TCF3/PBX10.0% (0/27)14.3% (7/49)0.046

For quantitative data, the results were presented as mean ± SEM; for qualitative data, the results were presented as percentage (positive/all).