Research Article

Chidamide and Radiotherapy Synergistically Induce Cell Apoptosis and Suppress Tumor Growth and Cancer Stemness by Regulating the MiR-375-EIF4G3 Axis in Lung Squamous Cell Carcinomas

Figure 5

Inhibition of miR-375 attenuated chidamide and chidamide plus radiation combinational treatment-induced suppression of cancer stemness in NCI-H2170 and NCI-H226 cells. (a) ALDEFLUOR assay was performed to evaluate the population of ALDH+ cells of NCI-H2170 and NCI-H226 cells with indicated treatment and the representative images were shown. (b) Statistic analysis of ALDH+ populations of NCI-H2170 and NCI-H226 cells with indicated treatment. All the data were statistically analyzed by Student’s t-test. ; ; and .
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