Impacts of LOC105371267 Variants on Breast Cancer Susceptibility in Northern Chinese Han Females: A Population-Based Case-Control Study

Table 4

MDR analysis for impact of LOC105371267 variants on risk of breast cancer.

Model	Training bal. acc.	Testing bal. acc.	CV consistency	Accuracy	Sensitivity	Specificity	OR (95% CI)
rs3931698	0.518	0.495	7/10	0.518	0.739	0.295	1.184 (0.911, 1.538)	0.206
rs3931698, rs6499221	0.531	0.481	6/10	0.529	0.476	0.583	1.269 (1.002, 1.607)	0.054
rs3852740, rs3931698, rs6499221	0.544	0.483	4/10	0.542	0.700	0.381	1.437 (1.121, 1.842)	0.005
rs111577197, rs3852740, rs3931698, rs8044565	0.559	0.480	7/10	0.556	0.629	0.482	1.576 (1.242, 2.001)	0.0001
rs111577197, rs3852740, rs3931698, rs6499221, rs8044565	0.574	0.497	10/10	0.570	0.602	0.538	1.761 (1.389, 2.232)	<0.0001

MDR: multifactor dimensionality reduction; SNP: single-nucleotide polymorphism; bal. acc.: balanced accuracy; CV: cross-validation; OR: odds ratio; CI: confidence interval. Note: ^ainteractions were validated by 1000 permutation tests. All p values in this study were two-tailed. Bold values mean statistical significance ().