Safety Analysis of Apatinib Combined with Chemotherapy in the Treatment of Advanced Gastric Carcinoma: A Randomised Controlled Trial

Figure 1

Comparison of serum indexes between the two groups before and after treatment (‾x ± s). (a) Comparison of MMP-9 levels before and after treatment. The abscissa represents before treatment and after treatment, and the ordinate represents the MMP-9 level (μg·L⁻¹). The MMP-9 levels in SG before and after treatment were (467.34 ± 39.56) μg·L⁻¹ and (219.46 ± 32.54) μg·L⁻¹, respectively. The MMP-9 levels in RG before and after treatment were (468.12 ± 38.74) μg·L⁻¹ and (269.56 ± 34.17) μg·L⁻¹, respectively. indicated an obvious difference in the MMP-9 levels of SG before and after treatment (t = 29.436, ). indicated an obvious difference in the MMP-9 levels of RG before and after treatment (t = 23.381, ). indicated an obvious difference in the MMP-9 levels between the two groups after treatment (t = 6.459, ). (b) Comparison of SIL-2R levels before and after treatment. The abscissa represented before treatment and after treatment, and the ordinate represented the SIL-2R level (pmol·L⁻¹). The SIL-2R levels in SG before and after treatment were (104.57 ± 16.54) pmol·L⁻¹ and (53.17 ± 12.34) pmol·L⁻¹, respectively. The SIL-2R levels in RG before and after treatment were (103.92 ± 17.12) pmol·L⁻¹ and (76.46 ± 10.83) pmol·L⁻¹, respectively. indicated an obvious difference in the SIL-2R levels of SG before and after treatment (t = 15.151, ); indicated an obvious difference in the SIL-2R levels of RG before and after treatment (t = 8.245, ); indicated an obvious difference in the SIL-2R levels between the two groups after treatment (t = 8.629, ).

(a)

(b)