Conversion Surgery for Patients with Advanced Gastric Cancer with Peritoneal Carcinomatosis

Table 3

Univariate and multivariate analysis of prognostic factors in GC patients with PC.

Variables	Patient numbers	1-year OS	Median OS (months)	value	Adjusted OR (95% CI)	value
Gender				0.732
Male	58	46.5%	18.8
Female	37	48.6%	14.6
Age				<0.001^∗	3.8 (1.1–12.8)	0.01^∗
≤65	54	55.7%	17.9
>65	41	26.8%	8.3
Stage				0.600
T2	12	41.6%	11.4
T3	32	43.7%	17.7
T4	51	50.7%	15.3
Lymph node status				0.690
N1	28	39.1%	10.3
N2	33	39.6%	14.6
N3	34	42.2%	12.6
PCI				0.019^∗	3.5 (1.3–10.6)	0.03^∗
<12	33	63.6%	14.6
>12	16	26.9%	9.2
Ascites				0.032^∗	2.8 (1.1–8.8)	0.02^∗
Yes	44	24.0%	7.9
No	51	61.4%	19.2
Complete of cytoreduction				0.036^∗	2.6 (1.8–6.6)	0.04^∗
CC-0	22	63.6%	18.8
CC-1	11	27.2%	10.0
CC-2	6	16.6%	8.3
Comorbidity				0.420
0	58	46.6%	16.4
1–2	32	39.4%	9.6
≧3	5	40.0%	10.8
ECOG				0.017^∗	2.16 (1.16–2.87)	0.043^∗
0	47	52.3%	14.4
1–2	33	36.3%	10.3
≧3	15	15%	4.1
UGI bleeding				0.359
Positive	32	37.5%	13.9
Negative	63	41.6%	14.6
Gastric outlet obstruction				0.139
Positive	31	35.1%	11.4
Negative	64	37.7%	12.6
Surgical complications					5.8 (3.9–21.2)	0.001^∗
Yes	14	21.4%	7.0
No	35	88.5%	20.7

GC: gastric cancer; PC: peritoneal carcinomatosis; OS: OR: odds ratio; PCI: peritoneal cancer index; CC: complete cytoreduction score; ECOG: Eastern Cooperative Oncology Group patient performance score; UGI: upper gastrointestinal.