Construction, Validation, and Visualization of Two Web-Based Nomograms to Predict Overall and Cancer-Specific Survival in Patients with Gastric Cancer and Lung Metastases

Table 3

Univariate and multivariate Cox proportional hazards regression analysis of patients with GCLM in the OS group.

Variables	Univariate Cox regression analysis		Multivariate Cox regression analysis
	HR (95% CI)		HR (95% CI)
Age
<60	Reference
≥60	1.044 (0.854–1.277)	0.671
Race
Black	Reference
Other	0.979 (0.658–1.457)	0.918
White	0.788 (0.586–1.061)	0.117
Sex
Female	Reference
Male	0.99 (0.799–1.225)	0.923
Histologic type
Adenocarcinoma	Reference
Signet ring cell	1.044 (0.786–1.388)	0.765
Intestinal type	1.358 (0.901–2.047)	0.144
Other	1.144 (0.873–1.498)	0.33
T stage
T1	Reference
T2	0.705 (0.459–1.083)	0.11
T3	0.944 (0.735–1.214)	0.656
T4	1.219 (0.969–1.535)	0.091
N stage
N0	Reference
N1	1.009 (0.820–1.243)	0.929
N2	0.961 (0.664–1.391)	0.833
N3	1.166 (0.790–1.721)	0.44
Grade
Grade I	Reference		Reference
Grade II	1.458 (0.850–2.501)	0.171	1.275 (0.738–2.201)	0.383
Grade III	1.864 (1.105–3.144)	0.02	1.896 (1.118–3.214)	0.018
Grade IV	1.238 (0.410–3.743)	0.705	0.942 (0.310–2.864)	0.916
Bone metastasis
No	Reference
Yes	1.075 (0.833–1.388)	0.58
Liver metastasis
No	Reference
Yes	1.309 (1.080–1.587)	0.006	1.440 (1.179–1.760)	<0.001
Brain metastasis
No	Reference
Yes	1.434 (0.806–2.550)	0.22
Primary site
Cardia	Reference
Fundus	1.487 (0.956–2.315)	0.079
Body	1.179 (0.792–1.754)	0.418
Gastric antrum	1.224 (0.893–1.676)	0.208
Lesser	1.211 (0.764–1.922)	0.416
Greater	1.182 (0.737–1.895)	0.488
Other	1.28 (0.995–1.646)	0.054
Radiotherapy
No	Reference
Yes	0.761 (0.606–0.955)	0.019	0.979 (0.770–1.244)	0.859
Chemotherapy
No	Reference
Yes	0.312 (0.253–0.384)	<0.001	0.292 (0.235–0.363)	<0.001
Surgery
No	Reference
Yes	0.835 (0.598–1.167)	0.291
Marital status
No	Reference
Yes	0.844 (0.694–1.025)	0.087
Insurance
No	Reference
Yes	1.076 (0.723–1.602)	0.718