Construction, Validation, and Visualization of Two Web-Based Nomograms to Predict Overall and Cancer-Specific Survival in Patients with Gastric Cancer and Lung Metastases

Table 4

Univariate and multivariate Cox proportional hazards regression analysis of patients with GCLM in the CSS group.

Variables	Univariate Cox regression analysis		Multivariate Cox regression analysis
	HR (95% CI)		HR (95% CI)
Age
<60	Reference
≥60	0.945 (0.759–1.176)	0.612
Race
Black	Reference		Reference
Other	0.823 (0.549–1.232)	0.343	0.916 (0.602–1.393)	0.681
White	0.707 (0.519–0.963)	0.028	0.883 (0.635–1.227)	0.458
Sex
Female	Reference
Male	0.976 (0.775–1.230)	0.837
Histologic type
Adenocarcinoma	Reference
Signet ring cell	1.064 (0.763–1.484)	0.715
Intestinal type	1.207 (0.798–1.825)	0.372
Other	1.152 (0.846–1.570)	0.368
T stage
T1	Reference		Reference
T2	0.594 (0.378–0.932)	0.024	0.71 (0.446–1.131)	0.149
T3	0.854 (0.648–1.124)	0.26	1.121 (0.840–1.497)	0.436
T4	1.088 (0.844–1.402)	0.513	1.15 (0.882–1.498)	0.302
N stage
N0	Reference
N1	0.922 (0.737–1.153)	0.475
N2	0.864 (0.498–1.500)	0.603
N3	0.865 (0.551–1.358)	0.528
Grade
Grade I	Reference
Grade II	1.282 (0.732–2.245)	0.385
Grade III	1.632 (0.950–2.806)	0.076
Grade IV	2.121 (0.813–5.530)	0.124
Bone metastasis
No	Reference
Yes		0.146
Liver metastasis
No	Reference		Reference
Yes	1.47 (1.186–1.821)	<0.001	1.524 (1.217–1.909)	<0.001
Brain metastasis
No	Reference
Yes	1.114 (0.610–2.033)	0.725
Primary site
Cardia	Reference		Reference
Fundus	1.593 (1.006–2.522)	0.047	1.312 (0.824–2.091)	0.253
Body	1.337 (0.880–2.030)	0.173	1.364 (0.882–2.108)	0.163
Gastric antrum	1.498 (1.067–2.105)	0.02	1.206 (0.846–1.718)	0.301
Lesser	1.185 (0.642–2.189)	0.587	1.409 (0.732–2.710)	0.305
Greater	2.024 (1.238–3.308)	0.005	2.315 (1.395–3.841)	0.001
Other	1.367 (1.035–1.805)	0.028	1.26 (0.932–1.704)	0.133
Radiotherapy
No	Reference
Yes	0.813 (0.640–1.033)	0.091
Chemotherapy
No	Reference		Reference
Yes	0.388 (0.311–0.484)	<0.001	0.398 (0.317–0.501)	<0.001
Surgery
No	Reference
Yes	0.715 (0.474–1.077)	0.109
Marital status
No	Reference		Reference
Yes	0.735 (0.592–0.912)	0.005	0.788 (0.629–0.988)	0.039
Insurance
No	Reference
Yes	0.954 (0.600–1.518)	0.843