Review Article
The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
Table 1
Autophagy-related miRNAs in Urological tumors.
| Tumor | MiRNA | Expression(up/down) | Effect | Target Gene | Ref |
| kidney cancer | | MiR-204 | Down | Promote autophagy | LC3 | [39] | MiR-100 | Down | Inhibit autophagy | MTOR | [40] | MiR-30a | Down | Promote autophagy | BECN1 | [41] | Hsa-miR-335 | Down | Promote autophagy | | [42] | MiR-497-5p | Down | Promote autophagy | ATG9A | [43] |
| Bladder cancer | | MiR-221 | Up | Inhibit autophagy | | [44] | MiR-222 | Up | Inhibit autophagy | MTOR | [45] | MiR-24-3p | Up | Promote autophagy | LC3 | [46] |
| Prostate cancer | | MiR-34a | Down | Inhibit autophagy | | [47] | MiR-361-5p | Up | Inhibit autophagy | LC3, BECN1 | [48] | MiR-205 | Up | Inhibit autophagy | TP53INP1 | [49] | MiR-146b | Up | Inhibit autophagy | MTOR | [50] | MiR-143 | Up | Inhibit autophagy | ATG2B | [51] | MiR-124, MiR-144 | Up | Inhibit autophagy | PIM1, LC3 | [52] | MiR-101 | Up | Inhibit autophagy | LC3 | [53] | MiR-96, MiR-34a | Up | Inhibit autophagy | ATG7 | [54] | MiR-34a | Down | Promote autophagy | ATG4B, BECN1, LC3 | [55] | MiR-26b | Up | Inhibit autophagy | ULK2, LC3 | [56] | MiR-212 | Down | Promote autophagy | SIRT1, LC3 | [57] | MiR-381 | Up | Promote autophagy | RELN, LC3, BECN1 | [58] | MiR-30a, MiR-205 | Down | Inhibit autophagy | LC3 | [59] | MiR-301a, | Up | Promote autophagy | NDRG2 | [60] | MiR-301b |
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