Review Article

The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer

Table 1

Autophagy-related miRNAs in Urological tumors.

TumorMiRNAExpression(up/down)EffectTarget GeneRef

kidney cancer
MiR-204DownPromote autophagyLC3[39]
MiR-100DownInhibit autophagyMTOR[40]
MiR-30aDownPromote autophagyBECN1[41]
Hsa-miR-335DownPromote autophagy[42]
MiR-497-5pDownPromote autophagyATG9A[43]

Bladder cancer
MiR-221UpInhibit autophagy[44]
MiR-222UpInhibit autophagyMTOR[45]
MiR-24-3pUpPromote autophagyLC3[46]

Prostate cancer
MiR-34aDownInhibit autophagy[47]
MiR-361-5pUpInhibit autophagyLC3, BECN1[48]
MiR-205UpInhibit autophagyTP53INP1[49]
MiR-146bUpInhibit autophagyMTOR[50]
MiR-143UpInhibit autophagyATG2B[51]
MiR-124, MiR-144UpInhibit autophagyPIM1, LC3[52]
MiR-101UpInhibit autophagyLC3[53]
MiR-96, MiR-34aUpInhibit autophagyATG7[54]
MiR-34aDownPromote autophagyATG4B, BECN1, LC3[55]
MiR-26bUpInhibit autophagyULK2, LC3[56]
MiR-212DownPromote autophagySIRT1, LC3[57]
MiR-381UpPromote autophagyRELN, LC3, BECN1[58]
MiR-30a, MiR-205DownInhibit autophagyLC3[59]
MiR-301a,UpPromote autophagyNDRG2[60]
MiR-301b