Research Article

Detection of MSH2 Gene Methylation in Extramammary Paget’s Disease by Methylation-Sensitive High-Resolution Melting Analysis

Table 1

Coefficient of correlation between MS-HRM and pyrosequencing methylation results.

ParametersMSH2 gene

Variable YMS-HRM
Variable XPyrosequencing
Sample size57
Correlation coefficient r0.9425
Significance level<0.0001
95% confidence interval for r0.9038 to 0.9658