miR-1224-3p Promotes Breast Cancer Cell Proliferation and Migration through PGM5-Mediated Aerobic Glycolysis

Figure 1

PGM5 expression is downregulated in breast cancer tissues. (a–c) PGM5 expression values were plotted and compared between 112 adjacent normal and 1073 tumor tissues based on the TCGA-BRCA database (a), 879 non-TNBC and 193 TNBC tissues based on the TCGA-BRCA database (b), and 144 normal and 1980 tumor tissues based on the METABRIC database (c) with the Mann–Whitney U test. (d) Kaplan–Meier survival curves for overall survival of 1959 patients with follow-up information according to the relative expression of PGM5 from the METABRIC dataset. (e, f) Kaplan–Meier survival curves for overall survival (e) and disease-free survival (f) of 145 patients in the GSE1456 database.

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