Plasma-Derived Exosomal microRNA-130a Serves as a Noninvasive Biomarker for Diagnosis and Prognosis of Oral Squamous Cell Carcinoma

Figure 1

miR-130a expression is significantly higher in OSCC patients. (a) Comparison of exosomal miR-130a expression levels between OSCC patients and healthy controls. (b) Comparison of miR-130a expression levels between OSCC tissues and paired adjacent noncancerous tissues. (c) ROC curves of exosomal miR-130a for discriminating OSCC patients from healthy controls. (d) Correlation between expression of miR-130a in plasma exosomes and that in OSCC tissues. (e) Comparison of miR-130a expression levels between OSCC patients at different TNM stages and healthy controls. (f) ROC curves of exosomal miR-130a for discriminating patients with early-stage OSCC from healthy controls.

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