GJA1 rs2071165 A > G Variant Increased Gastric Cancer Risk in Females of Northwest China: A Case-Control Study

Table 3

Association of genetic polymorphisms and gastric cancer prognosis.

	Genotype	OS^3						RFS^4
		Total	Event	Log-rank	MST^1	HR^2 (95% CI)		Total	Event	Log-rank	MST^1	Hr (95% CI)
rs2071165	GG	375	125	0.77	57	1.00		375	167	0.46	34	1.00
	AG	250	85		62	1.03 (0.75–1.41)	0.87	250	102		39.52	0.86 (0.64–1.15)	0.30
	AA	38	15		40	1.01 (0.54–1.87)	0.98	38	18		25	1.34 (0.77–2.32)	0.30
	Dominant	288	100	0.94	62	1.02 (0.76–1.39)	0.88	288	120	0.65	51	0.91 (0.69–1.20)	0.50
rs4530741	CC	223	79	0.95	56	1.00		223	99	0.75	33	1.00
	AC	319	110		59	1.05 (0.75–1.48)	0.76	319	138		37	0.99 (0.73–1.33)	0.93
	AA	120	36		43.12	1.03 (0.66–1.60)	0.91	120	49		25	1.09 (0.74–1.60)	0.67
	Dominant	439	146	0.80	62	1.05 (0.76–1.44)	0.78	439	187	0.58	37	1.01 (0.76–1.34)	0.93
rs6874309	AA	555	190	0.79	57	1.00		555	245	0.51	32	1.00
	TA	104	35		42.985	1.14 (0.75–1.71)	0.55	104	40		39.79	0.92 (0.631–1.34)	0.67
	TT	4	1		55	0.56 (0.08–1.09)	0.57	4	2		50	0.90 (0.20–3.67)	0.88
	Dominant	108	36	0.86	57	1.10 (0.73–1.65)	0.65	108	42	0.24	50	0.92 (0.64–1.33)	0.66

¹Median survival time, mean survival time was provided when MST could not be calculated; ²hazard ratio; ³overall survival; ⁴relapse free survival.