Bone Metastasis in Renal Cell Carcinoma Patients: Risk and Prognostic Factors and Nomograms

Table 2

Multivariate logistic regression analysis of BM in RCC patients.

Variables	OR (95% CI)	value
Grade
G1-2	Reference
G3-4	1.749 (1.388–2.204)	≤0.001
T stage
T1-2	Reference
T3-4	1.748 (1.379–2.216)	≤0.001
Histologic type
CP	Reference
CC	3.300 (1.459–7.466)	0.004
CD	4.216 (1.245–14.277)	0.021
PL	1.850 (0.762–4.490)	0.174
Tumor size, cm
<4	Reference
4–7	3.937 (2.745–5.648)	≤0.001
>7	3.510 (2.374–5.189)	≤0.001
N stage
N0	Reference
N1	2.654 (2.005–3.513)	≤0.001
Brain metastasis
No	Reference
Yes	4.283 (2.780–6.598)	≤0.001
Liver metastasis
No	Reference
Yes	3.309 (2.211–4.952)	≤0.001
Lung metastasis
No	Reference
Yes	5.351 (4.123–6.946)	≤0.001

BM, bone metastasis; RCC, renal cell carcinoma; CP, chromophobe; CC, clear cell; CD, collecting duct; PL, papillary.