TUC338 Promotes Diffuse Large B Cell Lymphoma Growth via Regulating EGFR/PI3K/AKT Signaling Pathway

<div>TUC338 activates EGFR/PI3K/AKT pathway via miR-28-5p. (a) luciferase reporter assay in DLBCL cells co-transfected with wild-type or mutant pmirGLO vector and miR-28-5p mimics. (b, c). qRT-PCR analysis of EGFR mRNA expression after miR-28-5p overexpression or silencing. (d) qRT-PCR analysis of EGFR mRNA level in paired DLBCL and normal tissues. (e) The correlation analysis between TUC338 and EGFR in DLBCL tissues. (f) Immunoblotting detecting the indicated protein levels in TUC338-silenced DLBCL cells transfected with miR-28-5p inhibitor. 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Journal of Oncology

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Figure 4

Figure 4: TUC338 Promotes Diffuse Large B Cell Lymphoma Growth via Regulating EGFR/PI3K/AKT Signaling Pathway 