Effect of the Number of Removed Lymph Nodes on Survival in Patients with FIGO Stage IB-IIA Cervical Squamous Cell Carcinoma following Open Radical Hysterectomy with Pelvic Lymphadenectomy: A Retrospective Cohort Study

Table 1

Association between number of RLN and clinical and pathological features.

Variable	Total N	RLN (PFS)		value	RLN (OS)		value
		6–21 N	21–55 N		6–16 N	17–55 N
Age, years				0.507			0.86
≤50	2013	1078	935		474	1539
>50	1114	597	517		259	855
Menopausal status				0.62			0.653
Premenopausal	2102	1119	983		498	1604
Postmenopausal	1025	556	469		235	790
FIGO stage				0.914			0.309
IB	1692	908	784		409	1283
IIA	1435	767	668		324	1111
Tumor diameter (cm)				<0.001			<0.001
≤4	2166	1206	960		545	1621
>4	791	377	414		148	643
Depth of stromal invasion				0.423			0.081
<1/2	1044	570	474		266	778
≥1/2	2031	1077	954		460	1571
LVSI				0.789			0.964
Negative	1863	1001	862		438	1425
Positive	1092	581	511		258	834
Parametrial invasion				0.198			0.615
Negative	2934	1580	1354		688	2246
Positive	143	69	74		36	107
Vaginal margin invasion				0.923			0.139
Negative	2958	1584	1374		686	2272
Positive	112	61	51		33	79

RLN, removed lymph nodes; PFS, progression-free survival; OS, overall survival; FIGO, Federation of Gynecology and Obstetrics; LVSI, lymph-vascular space invasion; RLN, removed lymph nodes.