Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7

<div>GNG7 inhibition rescued OST-mediated cytotoxic effects. (a, b) The expression of GNG7 in BrCa cells was confirmed by qPCR and western blotting. (c, d) The viability capacity of BrCa cells in the OST-treated, OST-treated + siRNA-NC, and OST-treated + siRNA-GNG7 group was detected by CCK-8 assay. (e) The proliferative capacity of BrCa cells in the OST-treated, OST-treated + siRNA-NC, and OST-treated + siRNA-GNG7 groups was detected by clonogenic assay. (f) The apoptosis rate of BrCa cells in the OST-treated, OST-treated + siRNA-NC, and OST-treated + siRNA-GNG7 groups was detected by flow cytometry. 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Journal of Oncology

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Figure 6

Figure 6: Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7 