E2F1 Maintains Gastric Cancer Stemness Properties by Regulating Stemness-Associated Genes

Figure 1

Increased expression of E2F1 in gastric cancer. (a) Increased E2F1 expression in gastric cancer tissue compared with normal stomach tissue. (b) GEPIA database demonstrates an increased expression level of E2F1 in gastric cancer tissues. (c) E2F1 mRNA expression level is higher in T3-4 stage patients compared with T1-2 stage patients. (d) E2F1 mRNA expression level is higher in poorly or moderately differentiated patients compared with well-differentiated patients. (e) Male patients with the higher expression level of E2F1 have a higher rate of tumor recurrence at a time point of two years after surgery. (f) Relationship between E2F1 expression and OS in gastric cancer patients.

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