E2F1 Maintains Gastric Cancer Stemness Properties by Regulating Stemness-Associated Genes

Figure 3

E2F1 contributes to stemness-property maintaining through regulating stemness-associated genes. (a) Downregulation of E2F1 in 7901 cells and overexpression of E2F1 in MKN-45 cells. (b) E2F1 increases migration and invasion ability in gastric cancer. (c) E2F1 regulates stemness-associated genes, such as OCT4, Nanog, BMI1, and CD44. (d) E2F1 regulates tumor sphere formation ability of gastric cancer.

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