Research Article

Prognostic Models for Nonmetastatic Triple-Negative Breast Cancer Based on the Pretreatment Serum Tumor Markers with Machine Learning

Table 2

The optimal prognostic cut-off value of each tumor marker determined by X-tile.

Tumor markerCut-offNo. of patients N (%)

CEA/(ng/mL)2.15<2.15167 (64.7)
≥2.1591 (35.3)
CA19-9/(U/mL)17.30<17.30202 (78.3)
≥17.3056 (21.7)
CA125/(U/mL)9.05<9.0564 (24.8)
≥9.05194 (75.2)
CA242/(U/mL)8.85<8.85217 (84.1)
≥8.8541 (15.9)
CA211/(ng/mL)1.15<1.15155 (60.1)
≥1.15103 (39.9)
CA15-3/(U/mL)16.00<16.00215 (83.3)
≥16.0043 (16.7)

CEA: carcinoembryonic antigen; CA: cancer antigen.